Do pacemaker cells have a refractory period?

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In heart pacemaker cells that act very similarly to neurons, another type of refractory period exists – the effective refractory period or ERP. This timespan occurs at the same time as the ARP but ends immediately before the RRP.

What is the refractory period of a pacemaker?

In AAI pacemakers, the first part of the refractory period is a programmable blanking period. The refractory period prevents the resetting by an R wave sensed in the atrium (ventriculoatrial cross talk). Its duration must be as long as the AR interval (between the atrial stimulus and the R wave),…

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Why do pacemakers have periods of repolarization?

These periods are essential to the appropriate pacemaker function as they prevent sensing of known but clinically inappropriate signals, such as the evoked potential and repolarization.

What is the effective refractory period of the cell?

This is termed the effective refractory period (ERP) or the absolute refractory period (ARP) of the cell. During the ERP, stimulation of the cell by an adjacent cell undergoing depolarization does not produce new, propagated action potentials. This occurs because fast sodium channels remain inactivated following channel closing during phase 1.

How long does the refractory period last in the ventricles?

The refractory period lasts almost as long as the contraction. FIGURE 14-23 Relationship between membrane potential changes and contraction in a ventricular muscle cell. The refractory period lasts almost as long as the contraction.


Cardiac Action Potential, Animation.


More about Do pacemaker cells have a refractory period?


1. Refractory periods, PMT | Cardiocases

The refractory period is an interval following a paced or sensed event in the chamber containing the pacing or sensing lead, during which the inhibited (SSI) or triggered (SST) pacemaker is not reset. In a VVI pacemaker, the first part of the refractory period is a programmable, absolutely refractory blanking period.

From www.cardiocases.com

3. 6: Pacemaker Timing Cycles and Special Features – Thoracic Key

Jun 04, 2016 · Timing cycles are based on cardiac events such as atrial- and ventricular-sensed and -paced events. Thus, appropriate pacemaker function depends on the ability of these devices to properly recognize atrial- and ventricular-sensed events. Timing cycles include different blanking periods, refractory periods, and intervals.

From thoracickey.com

4. Electrical Refractory (Recovery) Period following an Action Potential

Electrical Refractory Period of the Heart. Remember everything pertaining to nerve cells includes all muscle cells since they are excitable as well, including cardiac muscle. The non-pacemaker heart cells have a refractory period of 3/10ths of a second. So if one second is a thousand milliseconds, how many milliseconds is that refractory period?

From antranik.org

5. Heart Muscle Refractory Period – an overview – ScienceDirect

Heart Muscle Refractory Period. The effective refractory period (ERP) is the longest premature coupling interval (S1-S2) at a designated stimulus amplitude (usually 2× diastolic threshold) that results in failure of propagation of the premature impulse through a tissue. From: Clinical Arrhythmology and Electrophysiology, 2009. Related terms: Refractory Period; Action …

From www.sciencedirect.com

6. Timing Cycles – The Student Physiologist

Refractory Periods. PVAB is initiated by ventricular activity, and like the absolute refractory period in single-chamber devices it ensures that the device’s atrial channel doesn’t sense or respond to signals generated. PVARP is essentially a safeguard to prevent restarting of the AV delay timer. It begins after PVAB, with ventricular activity, and acts on the atrial channel of the device in …

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From thephysiologist.org

7. Refractory Period of the Heart – Body Function – 78 Steps Health

Mar 07, 2022 · Relationship between membrane potential changes and contraction in a ventricular muscle cell. The refractory period lasts almost as long as the contraction. FIGURE 14-23. Relationship between membrane potential changes and contraction in a ventricular muscle cell. The refractory period lasts almost as long as the contraction.

From www.78stepshealth.us

8. Non-Pacemaker Action Potentials – CV Physiology

Jan 25, 2021 · Effective Refractory Period. Once an action potential is initiated, there is a period of time comprising phases 0, 1, 2, 3 and early phase 4 that a new action potential cannot be initiated (see figure at top of page). This is termed the effective refractory period (ERP) or the absolute refractory period (ARP) of the cell. During the ERP, stimulation of the cell by an …

From www.cvphysiology.com

9. The Refractory Period – Neuroscience – NCBI Bookshelf

Thus, the refractory period limits the number of action potentials that a given nerve cell can produce per unit time. As might be expected, different types of neurons have different maximum rates of action potential firing due to different types and densities of ion channels. The refractoriness of the membrane in the wake of the action …

From www.ncbi.nlm.nih.gov


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